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Wikipedia entry: Androgens
Public domain internet encyclopaedia
Wikipedia [3/08]: Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors. This includes the activity of the accessory male sex organs and development of male secondary sex characteristics. Androgens, which were first discovered in 1936, are also called androgenic hormones or testoids. Androgens are also the original anabolic steroids. They are also the precursor of all estrogens, the female sex hormones. The primary and most well-known androgen is testosterone.
Full Wikipedia entry: Androgen
Wikipedia entry: C1-Inhibitor
Public domain internet encyclopaedia
Wikipedia [3/08]: C1-inhibitor (C1inh) is a serine protease inhibitor (serpin) protein, the main function of which is inhibition of the complement system. It circulates in blood at levels of around 0.25-0.45 g/l. C1-inh is the largest member among the serpin class of proteins. Remarkably, C1-inh has a 2-domain structure, unlike most family members. The serpin domain is similar to other serpins, and this part of C1-inh provides the inhibitory activity of C1-inh. The other domain, named N-terminal domain or N-terminal tail is not essential for C1-inh to inhibit proteinases. This domain has no similarity to other proteins. C1-inh is highly glycosylated glycosylated, bearing both N- and O-glycans. Especially the N-terminal domain is glycosylated heavily.
Full Wikipedia entry: C1-Inhibitor
Wikipedia entry: Danazol
Public domain internet encyclopaedia
Wikipedia [3/08]: Danazol is a derivative of the synthetic steroid ethisterone, a modified testosterone. Before becoming available as a generic drug, Danazol was marketed as Danocrine in the United States. It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis in the early 1970s. Although effective for endometriosis, its use is limited by its masculinizing side-effects. Its role as a treatment for endometriosis has been largely replaced by the GnRH agonists.
Full Wikipedia entry: Danazol
Wikipedia entry: Icatibant
Public domain internet encyclopaedia
Wikipedia [3/08]: Icatibant, a peptidomimetic consisting of ten amino acids, is an effective and specific antagonist of bradykinin B2 receptors. Bradykinin is a peptide-based hormone that is formed locally in tissues, very often in response to a trauma. It increases vessel permeability, dilates blood vessels and causes smooth muscle cells to contract. This hormone plays an important role in the mediation of pain.
Full Wikipedia entry: Icatibant
Wikipedia entry: Stanazolol/Winstrol
Public domain internet encyclopaedia
Wikipedia [3/08]: Stanozolol, commonly sold under the name Winstrol (oral) and Winstrol Depot (intra-muscular), was developed by Winthrop Laboratories in 1962. It is a synthetic anabolic steroid derived from testosterone, and has been approved by the FDA for human use.
Full Wikipedia entry: Stanazolol/Winstrol
Wikipedia entry: Tranexamic acid
Public domain internet encyclopaedia
Wikipedia [3/08]: Tranexamic acid (commonly marketed as Cyklokapron in the U.S. and as Transamin in Asia) is often prescribed for excessive bleeding. It is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis. It has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminoacaproic acid.
Full Wikipedia entry: Tranexamic acid
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Author: Jerini AG
Source: HAE-Network Status: 3/08 This list is frequently updated. Please send us your comments and suggestions by e-mail. |
